Welcome to the Lawson Lab!
We aim to learn under what context(s) parent-of-origin influences phenotype, and how diet affects relationships among metabolic traits.
We apply several complementary and integrated approaches including bench science, cultured cells, animal phenotyping and husbandry, and computational and systems biology.
We work with mouse models, which allow experimental manipulations of genotype and environmental factors under controlled conditions.
We integrate whole-genome sequence data with phenotypic data to understand the molecular mechanisms underlying the genetic architecture of metabolic traits.
We use our integrative systems biology approach to understand how different tissues interact in diabetes and obesity.