Publications

2020

Carson C and Lawson HA, Genetic background and diet affect brown adipose gene co-expression — metabolic associations. bioRxiv 2020

2019

Carson C, Miranda MA, Macias-Velasco JF, Gunawardana S, Hughes J, Oyama S, Kunzmann M, Schmidt H, Wayhart JP, and Lawson HA, Natural brown adipose expansion and remission of hyperglycemia in obese SM/J mice. bioRxiv 2019

Macias-Velasco JF, StPierre CL, Wayhart JP, Yin L, Spears L, Funai K, Miranda MA, Cheverud JM, Semenkovich CF, Lawson HA, Epistatic networks associated with parent-of-origin effects on metabolic traits. bioRxiv 2019

Miranda MA, StPierre CL, Macias-Velasco JF, Nguyen HA, Schmidt H, Agnello LT, Wayhart JP, and Lawson HA, Dietary iron interacts with genetic background to influence glucose homeostasis. Nutrition and Metabolism 2019:10(13)

2018

Miranda MA and Lawson HA, Ironing out the details: Untangling dietary iron and genetic background in diabetes. Nutrients 2018: 10(10)

Carson C and Lawson HA, The Epigenetics of Metabolic Syndrome. Physiological Genomics 2018: 50:947-955

Zhag Y, Xiong C, Kudelko M, Li Y, Wang C, Wong, Y, Tam V, Rai M, Cheverud J, Lawson HA, Sandell L, Chan W, Cheah, K, Sham P, Chan D, Early onset disc degeneration in SM/J mice is associated with ion transport systems and fibrotic changes. Matrix Biology 2018: 70:1234-139

Wang T, PehrssonEC, Purushotham D, Li D, Zhuo X, Zhang B, Lawson HA, Province MA, Krapp C, Lan Y, Coarfa C, Katz TA, Tang WY, Wang Z, Biswal S, Rajagopalan S, Colacino JA, Tsai ZT, Sartor MA, Neier K, Dolinoy DC, Pinto J Hamanaka RB, Mutlu GM, Patisaul HB, Aylor DL, Crawford GE, Wiltshire T, Chadwick LH, Duncun CG, Garton AE, McAllister KA, TaRGET II Consortium, Bartolomei MS, Walker CL, Tyson FL, The NIEHS TaRGET II Consortium and environmental epigenomics. Nature Biotechnology 2018: 35(3): 225-22

2017

Lawson HA, Zayed M, Wayhart JP, Fabbrini E, Love-Gregory L, Klein S, and Semenkovich CF, Physiologic and genetic evidence link Hemopexin to triglycerides in mice and humans. International Journal of Obesity 2017: 41:631-638

Wayhart JP and Lawson HA, Animal Models of Metabolic Syndrome, In: Animal Models for the Study of Human Disease, 2nd Edition, Michael Conn (ed), Elsevier, Cambridge MA 2017: 221-237

2015
Nikolskiy I, Conrad DF, Chun S, Fay JC, Cheverud JM, Lawson HA, Using whole-genome sequences of the LG/J and SM/J inbred mouse strains to prioritize quantitative trait genes and nucleotides. BMC Genomics 2015: 16:415

Paran CW, Verkerke AR, Heden TD, Park S, Zou K, Lawson HA, Song H, Turk J, Houmard JA, Funai, K, Reduced efficiency of sarcolipin-dependent respiration in myocytes from humans with severe obesity. Obesity 2015: 23(7):1440-9

2014

Cheverud JM, Lawson HA, Bouckaert K, Kossenkov AV, Showe LC, Cort L, Blankenhorn EP, Bedelbaeva K, Gourevitch D, Zhang Y, and Heber-Katz E, Fine-mapping quantitative trait loci affecting murine external ear tissue regeneration in the LG/J by SM/J advanced intercross line. Heredity 2014: 112(5):508-18

2013

Lawson HA, Animal Models of Metabolic Syndrome, In: Animal Models for the Study of Human Disease Michael Conn (ed), Elsevier, Cambridge MA 2013: 243-264

Lawson HA, Cheverud JM and Wolf JB, Genomic imprinting and parent-of-origin effects on complex traits. Nature Reviews Genetics 2013: 14(9): 609-617

Zhou X, Lowdon RF, Li D, Lawson HA, Madden HA, Costello JF, Wang T, Exploring long-range genome interations using the WashU Epigenome Browser. Nature Methods 2013: 10: 375-376

2012

Kraja AT*, Lawson HA*, Arnett DK, Borecki IB, Broeckel U, de la Fuentes L, Hunt SC, Province MA, Cheverud JM, Rao DC, Obesity-insulin targeted genes in the 3p26-25 region from human studies homologous to findings in LG/J and SM/J mice. Metabolism 2012: 61(8):1129-41. *co-corresponding authors

Wang JR, Pardo-Manuel de Villena F, Lawson HA, Cheverud JM, Churchill GA, McMillan L, Imputation of SNPs in inbred mice using local phylogeny. Genetics 2012: 190(2):449-58

2011

Cheverud JM, Lawson HA, Funk R, Zhou J, Blakenhorn EP, Heber-Katz E, Healing quantitative trait loci in a combined cross analysis using related mouse strain crosses. Heredity 2011: 108:441-446

Lawson HA, Cady JE, Partridge C, Wolf JB, Semenkovich CF, Cheverud JM, Genetic effects at pleiotropic loci are context-dependent with consequences for the maintenance of genetic variation in populations. PLOS Genetics 2011: 7(9): e1002256

Lawson HA, Lee A, Fawcett GL, Wang B, Pletscher LS, Maxwell TJ, Ehrich TH, Kenney-Hunt JP, Wolf JB, Semenkovich CF, Cheverud JM, The importance of context to the genetic architecture of diabetes-related traits is revealed in a genome-wide scan of a LG/J x SM/J murine model. Mammalian Genome 2011: 22(3-4):197-208

The Orangutan Genome Sequencing and Analysis Consortium (HA Lawson – member), Comparative and demographic analysis of orangutan genomes. Nature 2011: 469(7331):529-533

Norgard EA, Lawson HA, Pletscher LS, Wang B, Brooks VR, Wolf JB, Cheverud JM, Genetic factors and diet affect long bone length in the F34 LG,SM Advanced Intercross. Mammalian Genome 2011: 22(3-4): 178-196

Cheverud JM, Lawson HA, Fawcett GL, Wang B, Pletscher LS, Fox A, Maxwell TJ, Ehrich TH, Kenney-Hunt JP, Wolf JB, Semenkovich CF, Diet-dependent genetic and genomic imprinting effects on obesity in mice. Obesity 2011: 19(1): 160-170

2010

Lawson HA, Zelle KM, Fawcett GL, Wang B, Pletscher LS, Maxwell TJ, Ehrich TH, Kenney-Hunt JP, Wolf JB, Semenkovich CF, Cheverud JM, Genetic, epigenetic, and gene-by-diet interaction effects underlie variation in serum lipids in a LG/J x SM/J murine model. J Lipid Res 2010: 51(10): 2976-84

Lawson HA and Cheverud JM, Metabolic syndrome components in murine models. Endocr Metab Immune Disord Drug Targets 2010: 10(1): 25-40.

2007

King DC, Taylor J, Zhang Y, Cheng Y, Lawson HA, Martin J, Zhang Y, ENCODE groups for transcriptional Regulation and multispecies alignment, Chiaromonte. F, Miller W and Hardison RC, Finding cis-regulatory elements using comparative genomics: some lessons from ENCODE data. Genome Research 2007: 17(6): 775-786

Rhesus Macaque Genome Sequencing and Analysis Consortium (HA Lawson – member), The Rhesus Macaque Genome Sequence Informs Biomedical and Evolutionary Analyses. Science 2007: 16(5822): 222-234

2005

Weiss KM and Lawson HA, A Metaphoric Rise To Stardom. Evolutionary Anthropology 2005: 14(6): 213-217

2004

Shriver MD, Kennedy GC, Parra EJ, Lawson HA, Huang J, Akey JM and Jones KW, The Genomic Distribution of Human Population Substructure. Human Genomics 2004: 1(4): 274 – 286